It depends what you mean by biggest really! Generally it’s thought to be the ovum (or “egg cell”, which is the female sex cell, where all the sperms are trying to get to) because it has a large diameter (~1mm), but the longest cells are motor neurons. These are nerve cells, and can be up to 1m long!! They are very skinny though, so don’t have a big volume.
The giant squid has a nerve cell around 12m long – a lot bigger than an egg. There’s a deep sea amoeba called Gromia sphaerica that gets up to 38mm – that’s as big as a grape!
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